Idiopathic non-specific interstitial pneumonia: as an “autoimmune interstitial pneumonia”
نویسندگان
چکیده
منابع مشابه
Idiopathic Interstitial Pneumonia
Division of Pulmonary and Critical Care Medicine and Department of Radiology, University of Michigan Health System, and Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan; University of California, San Francisco, San Francisco, California; University of Washington, Seattle, Washington; Mayo Clinic, Scottsdale, Arizona; and Armed Forces Institute of ...
متن کامل[Idiopathic pulmonary fibrosis and non-specific interstitial pneumonia].
BACKGROUND Wild-type p53 is increased during cellular responses to various stresses. Mdm2, which is induced by p53, regulates p53 protein concentrations through the ubiquitin-proteasome pathway. AIM To investigate whether the Mdm2 mediated ubiquitination of p53 is associated with epithelial cell apoptosis in idiopathic pulmonary fibrosis (IPF). METHODS Immunohistochemistry and western blot ...
متن کاملSmoking-related idiopathic interstitial pneumonia.
Cigarette smoking is a key factor in the development of numerous pulmonary diseases. An international group of clinicians, radiologists and pathologists evaluated patients with previously identified idiopathic interstitial pneumonia (IIP) to determine unique features of cigarette smoking. Phase 1 (derivation group) identified smoking-related features in patients with a history of smoking (n=41)...
متن کاملLECTIN HISTOCHEMISTRY OF CHOLESTEROL CLEFT GRANULOMAS IN NON-SPECIFIC INTERSTITIAL PNEUMONIA (NSIP)
ABSTRACT Background: Cholesterol cleft granulomas with clusters of giant cells were noted to be a common feature of non-specific interstitial pneumonia (NSIP). Objective: This study aimed to define the cell populations involved in the granulomas. Methods: The granulomas of 16 patients with cryptogenic fibrosing alveolitis (five cases with the histological features ofNSIP, five with those ofUIP...
متن کاملIdiopathic nonspecific interstitial pneumonia: an interstitial lung disease associated with autoimmune disorders?
Recent evidence suggests that idiopathic nonspecific interstitial pneumonia (iNSIP) is a distinct clinical entity amongst other idiopathic interstitial pneumonias, and some data seem to suggest a possible pathogenetic role of autoimmunity. The aim of the present study was to assess if iNSIP might represent an early lung manifestation of an autoimmune disease. After initial review of cases found...
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ژورنال
عنوان ژورنال: Respiratory Medicine
سال: 2005
ISSN: 0954-6111
DOI: 10.1016/j.rmed.2004.07.001